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Par consГ©quent, le modafinil force en fait le cerveau Г  devenir plus Г©veillГ© lorsqu'il est utilisГ© pendant la journГ©e. On pense que le modafinil augmente les niveaux d'adrГ©naline dans le corps, ce qui pourrait expliquer pourquoi il est capable d'amГ©liorer les performances cognitives chez les personnes ayant de faibles niveaux de ce neurotransmetteur. Aux Г‰tats-Unis, le prix de gros du modafinil Г©tait d'environ 5,0 millions de dollars en 2017. Le modafinil agit sur l'axe hypothalamo-hypophyso-surrГ©nalien (HPA). On pense que le modafinil agit par des voies histaminergiques dans le cerveau. Modiodal Il a Г©tГ© dГ©montrГ© que le modafinil fonctionne mieux chez les personnes atteintes du syndrome des jambes sans repos ou d'affections similaires dues Г  une carence en dopamine. Le modafinil est utilisГ© dans le traitement de la somnolence dans la narcolepsie, la somnolence du travail postГ© et pour traiter la somnolence diurne excessive associГ©e Г  l'apnГ©e obstructive du sommeil. Des Г©tudes montrent que l'utilisation prolongГ©e du modafinil pourrait entraГ®ner une perte du rythme circadien normal. Le modafinil peut provoquer des effets secondaires tels que des Г©tourdissements, une bouche sГЁche, une perte d'appГ©tit et des maux de tГЄte. Les prГ©parations Г  libГ©ration prolongГ©e, cependant, peuvent avoir un dГ©lai plus long entre les doses, ce qui peut entraГ®ner de la somnolence. Modafinil Maroc Prix On ne sait pas si l'utilisation pendant la grossesse est sans danger. La dopamine, qui est principalement responsable de l'activation des systГЁmes de rГ©compense du cerveau et des actions motrices et du comportement, et l'acГ©tylcholine, qui est principalement responsable de l'attention et de l'apprentissage, sont toutes deux affectГ©es par le modafinil. Si vous avez des questions, vous devriez toujours parler avec votre fournisseur de soins de santГ©. Il est Г©galement utilisГ© dans le traitement de l'apnГ©e obstructive du sommeil chez les adultes et les enfants. Plus rarement, les individus peuvent souffrir d'hypertension artГ©rielle et de problГЁmes sexuels. Le modafinil est mГ©tabolisГ© par le CYP2C19 et le CYP3A4. Cela peut ГЄtre particuliГЁrement important pour ceux qui utilisent ce mГ©dicament rГ©guliГЁrement.

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